Spurs travel to Anfield on Sunday in a potentially season-defining clash with 15 points separating the two sides although the north London side have a game in hand.
"You cannot compare (Liverpool and Tottenham)," Pochettino said in an exclusive interview with Soccer Saturday.
"When he [Klopp] arrived at Liverpool, it was only about focussing to try to build a team to be able to compete and be a real contender with other teams.
"Our philosophy is completely different and we cannot compare our two projects, they are on a completely different level.
"In the last two transfer windows we cannot sign one player, it is like we are banned like has happened with some clubs now!
"Because we are focussed on different things, that is why we are different, and we must be focussed on operating in different ways, but always being competitive as football is the most important thing in this company.
"Because they have an unbelievable squad (they are challenging for the title) and they are a team who every season were adding more quality. So it is normal that Liverpool, Man City, Man Utd, Chelsea were building to win and be a real contender."