Manchester United will travel to London for their Premier League date with West Ham on Saturday evening.
The Red Devils suffered a damaging 3-1 home defeat to Paris Saint-Germain in the Champions League on Wednesday night and will be keen on bouncing back against David Moyes' side.
It will be a significant match as well as this will be the first time fans are allowed in the stadium, with as many as 2,000 home supporters set to take to the stands.
Coach Ole Gunnar Solskjaer will have to assess his team ahead of the match, with a number of players doubtful.
Marcus Rashford is one of the players who might miss the clash after he picked an injury during the PSG match.
The Englishman has a troubling shoulder injury, even though Solskjaer was optimistic he will be ready for the next match.
David de Gea is one other player whose fitness will be assessed ahead of the Hammers game, after showing signs of discomfort in midweek.
The Spanish picked an injury against Southampton last weekend but managed to shake it off and start against the French side.
There is good news though as Paul Pogba, Jesse Lingard, Scott McTominay and Anthony Martial will all be available for selection.
The Reds have been excellent on the road in recent weeks and picked their eighth win in a row away to Southampton.