Real Madrid host Barcelona in the latest edition of El Clasico, arguably the most-watched event of modern football.
Here's all you need to know ahead of a heavyweight showdown between Real Madrid and Barcelona, kicking off at 22:00 EAT.
What's at hand?
This is a huge match for all three teams at the top of LaLiga, with Atletico Madrid leading the way by a point from Barcelona, while Real Madrid are breathing down their necks a further two points back.
A win for either side would put them in with a big chance of claiming the title, while Diego Simeone and his men will be desperately hoping for a draw.
Barcelona still have Atletico Madrid to play before the end of the season, however, so Real really could be the team in the driving seat come Sunday morning.
Should Barca be favorites purely because of Messi?
Real look much more like a team than their Catalan rivals, and with the ever-strong midfield trio of Casemiro, Luka Modric, and Toni Kroos likely to boss proceedings in Madrid, it is difficult to see a way for Barcelona to win this match, short of Messi brilliance.
Messi's brilliance of course is always a possibility, but should that mean they are favorites for this match? Away in Madrid? Particularly given how well Eder Militao and Nacho played at the heart of the defense for Real on Tuesday, looking more than capable of filling in for Sergio Ramos and Raphael Varane.
A delve into the betting archives tells us that this is the biggest price Real Madrid have been to win a home league fixture over Barcelona since the 2012/13 season.
The odds now stand at 2.90 for Madrid win, and 2.40 for Koeman's men to bag the full points.
Real Madrid vs Barcelona predicted lineups
Real Madrid: Courtois; Vazquez, Militao, Nacho, Mendy; Casemiro, Kroos, Modric; Asensio, Benzema, Vinicius Jr
Barcelona: Ter Stegen; Mingueza, Lenglet, De Jong; Dest, Busquets, Pedri, Alba; Dembele, Messi, Griezmann
El Clasico prediction
The world will again be watching as both teams look to usurp Atletico at the top of the table, continuing one of the most captivating title races in years.
Both teams are expected to attack, given the weakness of each defense, and it'll be interesting to see whether Ronald Koeman's 3-4-3 system continues to get the best out of his front three.
Madrid have only lost two Clasico's under Zinedine Zidane's guidance and the 3-1 win at Camp Nou earlier this season will be on the minds of both teams.
Ultimately, three points are the only acceptable outcome for both sides - which could, inevitably, lead to a draw, hopefully of the entertaining variety.
Or Madrid might just nick it!
💶 Best bet: Real Madrid win or draw at FT
📲 Follow Real Madrid vs Barcelona live on Futaa!