Villarreal will host Manchester United at Estadio de la Ceramica in the reverse fixture of the Champions League tonight.
A win for United will see them go through to the knockout rounds with a game to spare. The Red Devils head into Matchday 5 top of Group F on goal difference, and level on seven points with Unai Emery's side.
Both Atalanta and Young Boys can mathematically reach the last 16, sitting in third and fourth with five points and three points respectively.
Michael Carrick has named his XI as interim manager after Ole Gunnar Solskjaer's departure on Sunday morning. Jadon Sancho and Donny van de Beek have been handed a start while midfielder Bruno Fernandes starts from the bench.