The German will start alongside Sokratis Papastathopoulos at centreback, with Sead Kolasinac and Maitland-niles completing the backline with Bernd Leno keeping his place in goal.
Granit Xhaka and Lucas Torreira will anchor the midfield with Alex Iwobi and Henrikh Mkhitaryan taking care of the wings.
Arsenal's top scorer this season Pierre-Emerick Aubameyang is also back in the side after missing the midweek defeat to Wolves and will start alongside Alexandre Lacazette as the Gunners target a precious three points.
Mesut Ozil completely misses out.
⬇️ Predict 6 EPL football scores with Futaa6 and you could win the $10,000 Jackpot, best of all it’s completely free to play every week in the Futaa Android App Download it now to play!