Action across Europe is set to continue through the week with a number of matches lined up.
The English Premier League takes a break, but there's one match on the cards to wind up Matchday 17 before attention shifts to the Carabao and the FA Cup.
There will be action though in LaLiga and the Serie A, with a number of exciting clashes.
We take a look at some of the top fixtures not to miss this week.
Southampton vs Liverpool (Monday)
Liverpool head to St. Mary's Stadium on Monday night hoping to pick their first win in three games. It will be a tough encounter against a Southampton side that has been one of the best teams in the league this season, sitting ninth in the Premier League standings.
A win for Jurgen Klopp's side will see them open a three-point gap over second-placed Man United, who will have a match at hand.
The boss looks ahead to a big test at St Mary's tonight 💬 pic.twitter.com/lkzERPdxx4— Southampton FC (@SouthamptonFC) January 4, 2021
Athletic Bilbao vs Barcelona (Tuesday)
Barcelona have found it rough against Bilbao in recent matches, winning only once in the last five matches.
Ronald Koeman's side recorded a 1-0 win over Huesca on Sunday night, a victory that lifted them to fifth on the log 10 points off league leaders Atletico Madrid, who have a match at hand.
Milan vs Juventus (Wednesday)
Serie A league leaders AC Milan are the only unbeaten side across Europe's top five leagues. Their 2-0 win over Benevento on Sunday evening saw them move to 37 points, 10 ahead of Andrea Pirlo's Juventus.
They could stake their claim at the title with a win over Juventus, who struggled but eventually won 4-1 against Udinese on Sunday night as well.
Manchester United vs Man City (Wednesday)
A Manchester derby in the Carabao Cup semis should be a cracker of a match. In-form United will be favourites against a City side that has been hit by COVID-19, which has seen a number of their first-team players sit out of key matches.
They've however done impressively well, with a 3-1 win over Chelsea at Stamford Bridge giving them a morale boost ahead of the match.
Aston Villa vs Liverpool (Friday)
Liverpool will be in action again on Friday, this time in the FA Cup. Villa have been impressive in recent games and will be a tough nut to crack for Klopp's men.