Virgil van Dijk has withdrawn from the Netherlands' squad for their European Qualifier against Estonia on Tuesday for personal reasons.
A statement on the Netherlands Football Team website noted: “National team coach Ronald Koeman cannot rely on VirgiI van Dijk on Tuesday against Estonia. The captain of the Dutch national team has to let go of the game due to personal circumstances and has since left the Orange training camp.”
Van Dijk captained the Netherlands in their 0-0 draw with Northern Ireland on Saturday that secured qualification for next summer's European Championships.
No further information has been given by the Dutch FA for his withdrawal, other than to simply say Van Dijk will not be available for Tuesday's clash at the Johan Cruyff Arena.
Van Dijk is the fifth Liverpool player to withdraw from international duty in the past week.
England duo Jordan Henderson and Joe Gomez both withdrew from the England squad after their win against Montenegro on Thursday.
Others are Egyptian star Mo Salah also missed national team fixtures against Kenya and Comoros as well as Scotland captain Andy Robertson also withdrew after picking up a knock in Liverpool's 3-1 win against Manchester City last week.