Goalkeeper David de Gea is fit for Manchester United, while Aaron Wan-Bissaka returns in what looks like a back five for hosts Manchester United.
Anthony Martial who has been out with an injury returns to the starting team but will have to be contented with a place on the bench.
Liverpool, on the other hand, is without Mo Salah, who is injured, so Divock Origi comes in. Goalkeeper Alisson returns to the starting line-up with Adrian moving to the bench.
Manchester United Starting XI: De Gea; Wan-Bissaka, Tuanzebe, Lindelof, Maguire, Young; Fred, McTominay, Pereira; James, Rashford.
Substitutes: Romero, Rojo, Williams, Garner, Mata, Greenwood, Martial.
Liverpool Starting XI: Alisson; Alexander-Arnold, Matip, van Dijk, Robertson; Henderson, Fabinho, Wijnaldum; Origi, Firmino, Mane.
Substitutes: Adrian, Lovren, Milner, Keita, Gomez, Oxlade-Chamberlain, Lallana.