Paris Saint-Germain was held to a goalless stalemate at the Parc des Princes by Nice in a Ligue 1 encounter staged on Wednesday night.
It was a dull performance with a section of the club fans asking if Lionel Messi was fit for the game after being fielded despite skipping training on Tuesday with a bout of gastroenteritis.
The game came a day after the Argentine claimed a record-extending seventh Ballon d'Or; the result seeing PSG stay on top of the standings with 41 points from 16 games.
In the other games, Marseille leapfrogged Stade Rennais into second place with a 1-0 win at Nantes as the Rennes side slumped to a 2-1 home defeat against champions Lille.
In Italy, Junior Messias scored twice on his first AC Milan start as the Rossoneri thrashed Andriy Shevchenko's Genoa 3-0 to close the gap to Serie A leaders Napoli to one point.
On the same day, Sassuolo fought back from two goals down to draw 2-2 with Napoli, leaving the Partenopei on 36 points, one ahead of second-placed Milan.
In Spain, Karim Benzema scored again as Real Madrid beat Athletic Club 1-0 to go seven points clear at the top of Laliga. Real however have a game more than second-placed neighbors Atletico Madrid.
Meanwhile, in the Copa del Rey, La Liga sides Real Sociedad, Real Mallorca, Espanyol, Sevilla, and Real Betis all won against lower-division clubs to advance to the next round.