Mike Mutebi has made several changes to the team that lost 3-0 to Congolese side AS Otoho last weekend in Owando, Congo.
The coach has dropped Lawrence Bukenya, Eric Ssenjobe, Filbert Obenchan and Mike Mutyaba from the starting team.
The former two have been left out of the match day squad while Mutyaba and Obenchan watch from the bench.
Their positions have been taken up by defender Hassan Musana, Allan Kyambadde, Muzamir Mutyaba and youngster Peter Magambo.
The City lads need to score four unanswered goals to progress to the group stage of the Confederations cup.
KCCA FC XI - Charles Lukwago (GK); Magambo Peter, Awany Dennis Timothy (c), Musana Hassan, Kizza Mustafa; Gift Ali Abubakar, Poloto Julius; Henry Patrick Kaddu, Okello Allan, Muzamir Mutyaba, Kyambadde Allan