Express FC will have another chance to repay Police after that 2-0 loss in the league on Monday at Wankulukuku that caused the entire technical bench to be sacked.
The two sleeping giants have been paired against each other in the 2018-19 Stanbic Uganda Cup round of 16.
The draws were held on Wednesday morning at FUFA house in Mengo, Kampala.
In the other draws, high-flying FUFA Big League side Wakiso Giants has will host Tooro United in Bugembe.
BUL FC play host to Bukedea Town Council, Vipers take on Kiboga Young, URA face Bright Stars in an all-premier league affair as Onduparaka travel to Lugogo to face Proline.
The games will be played between Thursday 14th and Tuesday 19th February.
Round of 16 draws;
Express FC Vs. Police FC
Bul FC Vs. Bukedea Town
Wakiso Giants FC Vs. Tooro UTD
Kitara FC Vs. Kyetume FC
Vipers SC Vs. Kiboga Young FC
URA FC Vs. Bright Stars FC
Proline FC Vs. Onduparaka FC
Nebbi Central FC Vs. Nkambi FC